Hi Kevin,
Were the USB cables the same in both cases? I've seen my laptop recognise both my DSIs, but they won't operate if I've forgotton to power up the USB hub on my scope (distance between computer and scope is 5m on a repeater cable + 0.5m to hub). The DSI's draw alot of power from the USB line, so best to use a powered hub on the scope to make sure the power supply is going to be adequate.
I have XP on my laptop, and it will run the DSIs from any of the ports, but it will go through the "found new hardware routine" for every combination you make; best to keep things connected the same way each time.
Hope this helps,
Jon
8" Mead LX-90 + DSI III
Isle of Wight